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The He Group@HKU

Home
Research
Publications
2026
2025
2024
2023
2022
2021
Supervised Work
Team Members
Postdoctoral Fellows
Graduate Students
MPhil Students
Undergraduate Students
More
Alumni
Jian He
Group Activities
Contact
4c6459a27c1f84c45de9e4319a58914e.jpg
  • Publications
  • 2026
  • 2025
  • 2024
  • 2023
  • 2022
  • 2021
  • Supervised Work

27

Wu, Q.-F.; Chen, G.; He, J.; Yu, J.-Q. Catalytic, Enantioselective, C–H Functionalization to Form Carbon–Carbon Bonds. Org. React. 2019, 100, 671−748.


26

He, J.; Chen, C.; Fu, G. C.; Peters, J. C. Visible-Light-Induced, Copper-Catalyzed Three-Component Coupling of Alkyl Halides, Olefins, and Trifluoromethylthiolate to Generate Trifluoromethyl Thioethers. ACS Catal. 2018, 8, 11741–11748.


25

Shao, Q.; Wu, Q.; He, J.; Yu, J.-Q. Enantioselective γ-C(sp3)–H Activation of Alkyl Amines via Pd(II)/Pd(0) Catalysis. J. Am. Chem. Soc. 2018, 140, 5322–5325.


24

He, J.; Wasa, M.; Chan, K. S. L.; Shao, Q.; Yu, J.-Q. Palladium-Catalyzed Transformations of Alkyl C–H Bonds. Chem. Rev. 2017, 117, 8754–8786.


23

Shao, Q.; He, J.; Wu, Q.; Yu, J.-Q. Ligand-Enabled γ-C(sp3)–H Cross-Coupling of Nosyl-Protected Amines with Aryl- and Alkylboron Reagents. ACS Catal. 2017, 7, 7777–7782.


22

Wang, H.-W.; Lu, Y.; Zhang, B.; He, J.; Xu, H.-J.; Kang, Y.-S.; Sun, W.-Y.; Yu, J.-Q. Ligand-Promoted Rhodium(III)-Catalyzed ortho-C–H Amination of Benzamides with Free Amines. Angew. Chem. Int. Ed. 2017, 56, 7449–7453.


21

Pei, Q.-L.; Che, G.-D.; Zhu, R.-Y.; He, J.; Yu, J.-Q. An Epoxide-Mediated Deprotection Method for Acidic Amide Auxiliary. Org. Lett. 2017, 19, 5860–5863.


20

Zhu, R.-Y.; Saint-Denis, T. G.; Shao, Y.; He, J.; Sieber, J. D.; Senanayake, C. H.; Yu, J.-Q. Ligand-Enabled Pd(II)-Catalyzed Bromination and Iodination of C(sp3)–H Bonds. J. Am. Chem. Soc. 2017, 139, 5724–5727.


19

Hoyt, C. B.; Lee, L.-C.; He, J.; Yu, J.-Q.; Jones, C. W. Selective C(sp3)–H Monoarylation Catalyzed by a Covalently Cross-Linked Reverse Micelle-Supported Palladium Catalyst. Adv. Synth. Catal. 2017, 359, 3611–3617.


18

He, J.; Shao, Q.; Wu, Q.; Yu, J.-Q. Pd(II)-Catalyzed Enantioselective C(sp3)–H Borylation. J. Am. Chem. Soc. 2017, 139, 3344–3347.


17

Fu, H.; Shen, P.-X.; He, J.; Zhang, F.; Li, S.; Wang, P.; Liu, T.; Yu, J.-Q. Ligand-Enabled Alkynylation of C(sp3)–H Bonds with Palladium(II) Catalysts. Angew. Chem. Int. Ed. 2017, 56, 1873–1876.


16

Wu, Q.-F.; Shen, P.-X.; He, J.; Wang, X.-B.; Zhang, F.; Shao, Q.; Zhu, R.-Y.; Mapelli, C.; Qiao, J. X.; Poss, M. A.; Yu, J.-Q. Formation of α-Chiral Centers by Asymmetric β-C(sp3)–H Arylation, Alkenylation, and Alkynylation. Science 2017, 355, 499–503.


15

Wang, P.; Li, G.-C.; Jain, P.; Farmer, M.; He, J.; Shen, P.-X.; Yu, J.-Q. Ligand-Promoted meta-C–H Amination and Alkynylation. J. Am. Chem. Soc. 2016, 138, 14092–14099.


14

Lee, L.-C.; He, J.; Yu, J.-Q.; Jones, C. W. Functionalized Polymer-Supported Pyridine Ligands for Palladium-Catalyzed C(sp3)–H Arylation. ACS Catal. 2016, 6, 5245–5250.


13

Jiang, H.;† He, J.;† Liu, T.; Yu, J.-Q. Ligand-Enabled γ-C(sp3)–H Olefination of Amines: En Route to Pyrrolidines. J. Am. Chem. Soc. 2016, 138, 2055–2059.


12

He, J.; Jiang, H.; Takise, R.; Zhu, R.-Y.; Chen, G.; Dai, H.-X.; Dhar, T. G. M.; Shi, J.; Zhang, H.; Cheng, P. T. W.; Yu, J.-Q. Ligand-Promoted Borylation of C(sp3)−H Bonds with Palladium(II) Catalysts. Angew. Chem. Int. Ed. 2016, 55, 785–789.


11

Zhu, R.-Y.; Tanaka, K.; Li, G.-C.; He, J.; Fu, H.-Y.; Li, S.-H.; Yu, J.-Q. Ligand-Enabled Stereoselective β-C(sp3)−H Fluorination: Synthesis of Unnatural Enantiopure anti-β-Fluoro-α-Amino Acids. J. Am. Chem. Soc. 2015, 137, 7067–7070.


10

He, J.; Takise, R.; Fu, H.; Yu, J.-Q. Ligand-Enabled Cross-Coupling of C(sp3)–H Bonds with Arylsilanes. J. Am. Chem. Soc. 2015, 137, 4618–4621.


9

He, J.; Shigenari, T.; Yu, J.-Q. Palladium(0)/PAr3-Catalyzed Intermolecular Amination of C(sp3)–H Bonds: Synthesis of β-Amino Acids. Angew. Chem. Int. Ed. 2015, 54, 6545–6549.


8

Chen, G.; Shigenari, T.; Jain, P.; Zhang, Z.; Jin, Z.; He, J.; Li, S.; Mapelli, C.; Miller, M. M.; Poss, M. A.; Scola, P. M.; Yeung, K.-S.; Yu, J.-Q. Ligand-Enabled β-C–H Arylation of α-Amino Acids Using a Simple and Practical Auxiliary. J. Am. Chem. Soc. 2015, 137, 3338–3351.


7

Zhu, D.; Yang, G.; He, J.; Chu, L.; Chen, G.; Gong, W.; Chen, K.; Eastgate, M.; Yu, J.-Q. Ligand-Promoted Ortho-C–H Amination with Pd Catalysts. Angew. Chem. Int. Ed. 2015, 54, 2497–2500.


6

Zhu, R.-Y.; He, J.; Wang, X.-C.; Yu, J.-Q. Ligand-Promoted Alkylation of C(sp3)–H and C(sp2)–H Bonds. J. Am. Chem. Soc. 2014, 136, 13194–13197.


5

Deng, Y.; Gong, W.; He, J.; Yu, J.-Q. Ligand-Enabled Triple C–H Activation Reactions: One-Pot Synthesis of Diverse 4-Aryl-2-Quinolinones from Propionamide. Angew. Chem. Int. Ed. 2014, 53, 6692–6695.


4

He, J.; Li, S.; Deng, Y.; Fu, H.; Laforteza, B. N.; Spangler, J. E.; Homs, A.; Yu, J.-Q. Ligand-Controlled C(sp3)–H Arylation and Olefination in Synthesis of Unnatural Chiral α-Amino Acids. Science 2014, 343, 1216–1220.


3

He, J.; Wasa, M.; Chan, K. S. L.; Yu, J.-Q. Palladium(0)-Catalyzed Alkynylation of C(sp3)–H Bonds. J. Am. Chem. Soc. 2013, 135, 3387–3390.


2

Wasa, M.; Chan, K. S. L.; Zhang, X.-G.; He, J.; Miura, M.; Yu, J.-Q. Ligand-Enabled Methylene C(sp3)–H Bond Activation with a Pd(II) Catalyst. J. Am. Chem. Soc. 2012, 134, 18570–18572.


1

He, J.; Lu, Z.; Chai, G.; Fu, C.; Ma, S. CuCl-Catalyzed Stereoselective Conjugate Addition of Grignard Regents to 2,3-Allenoates. Tetrahedron 2012, 68, 2719–2724.

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